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Methotrexate: Uses, Dosage, Side Effects - Drugs.com
Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. ...

Methotrexate - Wikipedia
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions.

Methotrexate: MedlinePlus Drug Information
Methotrexate is used to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) that cannot be controlled by other treatments.

Methotrexate (Trexall): Side Effects, Dosages, Treatment ...
Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens, and hydatidiform mole.. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents.

Methotrexate (Anti-Rheumatic) Oral : Uses, Side Effects ...
Methotrexate has rarely caused serious (sometimes fatal) side effects. Therefore, this medication should be used only to treat cancer or severe diseases caused by an overactive immune system (such ...

methotrexate, Rheumatrex, Trexall: Drug Facts, Side Effects ...
Methotrexate should not be used in pregnancy, as it can be toxic to the embryo and can cause fetal defects and spontaneous abortion (miscarriage).It should be discontinued prior to conception if used in either partner.

Methotrexate (By mouth) - National Library of Medicine ...
Methotrexate is used alone or together with other medicines to treat several types of cancer such as breast, head and neck, lung, blood, bone, lymph node, and uterus cancers.

Methotrexate Side Effects | RA Treatment
Methotrexate is one of the most effective and widely used medications for treating rheumatoid arthritis (RA) and other inflammatory types of arthritis. It’s also one of the safest arthritis drugs, insist rheumatologists, despite a common misconception among many patients and even some primary care ...

Methotrexate Side Effects in Detail - Drugs.com
Along with its needed effects, methotrexate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking methotrexate: Some side effects ...

A Guide to Methotrexate Medication
Methotrexate (brand names Rheumatrex, Trexall, Otrexup, Rasuvo) is commonly prescribed to treat rheumatoid arthritis and certain other rheumatic conditions. Methotrexate was approved by the FDA in 1988 for the treatment of rheumatoid arthritis.



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       *** News Filter: "Methotrexate"



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Text message reminders improve methotrexate adherence in RA
Weekly text message reminders have a positive impact on methotrexate adherence among adult patients with rheumatoid arthritis, according to findings in Arthritis Care & Research. “The strong association between poor adherence in RA and worsening ...

Review Finds Better Efficacy of Biologics in Trials Without Placebo
The Center for Biosimilars
The review included randomized clinical trials in those with inadequate response to methotrexate and other disease-modifying anti-rheumatic drugs. However, randomized clinical trials involving monotherapy, methotrexate-naïve patients, or those who ...

MedPage Today

Infection Rates Stable with Rituximab
MedPage Today
Rates of serious infections among patients with rheumatoid arthritis (RA) treated with rituximab (Rituxan) remained stable through 5 years of real-world use, researchers reported. In an observational study that followed 989 patients for up to 5 years ...

Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after ...
MD Linx
They noted an association of several metabolites with achieving sDFR in early RA patients treated-to-target with a tocilizumab- or methotrexate-based strategy. The metabolic profiles, by analyzing relevant transcripts and proteins within the same ...

Rheumatology Advisor

Autoantibody Status Not Associated With Early Remission in Rheumatoid Arthritis
Rheumatology Advisor
For patients with newly diagnosed rheumatoid arthritis (RA) being treated with methotrexate (MTX), autoantibody status is not associated with early remission, according to study results published in Rheumatology. These results indicate that MTX is an ...

Rheumatology Advisor

Text Message Reminders Improve Rheumatoid Arthritis Treatment Adherence
Rheumatology Advisor
Methotrexate (MTX) treatment adherence appears to be higher in individuals with rheumatoid arthritis (RA) who receive text message reminders than in those who do not, according to findings published in Arthritis Care & Research. Study investigators ...

Rheumatology Advisor

Worse Clinical, Ultrasonographic Response in Rheumatoid Arthritis With Obesity
Rheumatology Advisor
Patients with obesity and rheumatoid arthritis (RA) experienced worse clinical and ultrasonographic outcomes compared with patients without obesity, according to study results published in The Journal of Rheumatology. Investigators performed a post hoc ...

Business Wire (press release)

Horizon Pharma plc Initiates Clinical Trial to Evaluate KRYSTEXXA® (pegloticase injection) with Methotrexate to ...
Business Wire (press release)
“Real-world feedback from the medical community informed our selection of methotrexate as the immunomodulator in this study,” said Paul Peloso, M.D., M.Sc., vice president and therapeutic area head, rheumatology, Horizon Pharma plc. “MIRROR ...

and more »

Combo Therapy Not Needed if Low RA Disease Activity Achieved
Monthly Prescribing Reference
HealthDay News — Once low rheumatoid arthritis (RA) disease activity is achieved with tocilizumab (TCZ) plus methotrexate (MTX), patients can discontinue MTX without significant disease worsening, according to a study published in the August issue of ...

and more »



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