Rheumatology News, Info, Symptoms

* Rheumatology101 SEARCH *

*Filter: "Autoimmune-disease"

Autoimmune Diseases: Types, Symptoms & Treatments
Living with an autoimmune disease like lupus, rheumatoid arthritis and multiple sclerosis can be complex and serious. Although there are no cures for these diseases, many of their symptoms can be treated, and sometimes they go into remission.

Autoimmune Diseases: Symptoms, Causes & Treatments - Healthline
Learn about autoimmune diseases, including common symptoms, causes, and treatments. Discover types like rheumatoid arthritis, lupus, and more.

List of autoimmune diseases, with symptoms and treatments
There are more than 100 autoimmune diseases that scientists know about today. This article provides a list of autoimmune diseases and some of their symptoms.

Autoimmune disease - Wikipedia
Autoimmune diseases represent a vast and diverse category of disorders that, despite their differences, share some common symptomatic threads. [1] These shared symptoms occur as a result of the body's immune system mistakenly attacking its own cells and tissues, causing inflammation and damage.

Autoimmune Diseases: Causes, Symptoms, and Treatments - WebMD
Learn about the causes, symptoms, and treatments of autoimmune diseases in this informative guide. Take charge of your health and find the support you need.

List of autoimmune diseases - Wikipedia
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body.

Autoimmune Disease List: Symptoms, Causes & Treatments
Explore our complete list of autoimmune diseases, with in-depth information on symptoms, causes, risk factors, and treatment options.

Autoimmune Disease: Types, Symptoms, and More - Verywell Health
Autoimmune diseases occur when the immune system mistakenly attacks the body’s own cells. There are more than 100 different autoimmune diseases, affecting over 23.5 million Americans.

Autoimmune Diseases - National Institute of Environmental Health ...
Scientists know about more than 80 autoimmune diseases. Some are well known, such as type 1 diabetes, multiple sclerosis, lupus, and rheumatoid arthritis, while others are rare and difficult to diagnose. With unusual autoimmune diseases, patients may suffer years before getting a proper diagnosis. Most of these diseases have no cure.

10 Autoimmune Diseases – When to Worry and When to See a Doctor
Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues. Symptoms vary widely depending on the condition and the organs affected. Here is a guide to 10 common autoimmune diseases, including what they are, typical symptoms, when to worry and when to see a doctor.

* Rheumatology101 LATEST NEWS *

*Filter: "Autoimmune-disease"

Joe Manganiello Spent 7 Years Anticipating His Death During Debilitating Autoimmune Disease Battle  E! News
One woman, three autoimmune diseases: CAR-T therapy vanquishes ultra-rare disease trio  Nature
I'm a doctor, here are the hidden signs you could have an autoimmune disease  Newsweek
Can Being a People-Pleaser Really Cause an Autoimmune Disease?  Everyday Health
How did Bryan Johnson end up with an autoimmune disease?  Northeastern Global News
Could a Cancer Treatment Cure Autoimmune Diseases?  The New Yorker
Why Carrie Ann Inaba Says Getting This Autoimmune Disease Diagnosis Was a ‘Relief’  The Healthy
Woman with three deadly diseases has ‘remarkable’ recovery after cell therapy  The Guardian
A Cancer Treatment That Does More Than Scientists Thought  The Atlantic
Scientists explore new frontier in autoimmune disease treatment by resetting 'rogue' cells  PBS
Roswell Park Offering CAR T Trial for Autoimmune Conditions  Roswell Park Comprehensive Cancer Center
Can 'being a b****' really prevent autoimmune disease? Viral meme may hold some truth  The Jerusalem Post
Woman Was Misdiagnosed With Type 2 Diabetes and Landed in ER. Now She’s Running a Marathon  TODAY.com
Dear Doctor: What is birdshot chorioretinopathy, and how is it treated?  OregonLive.com
Bryan Johnson, the man who wants to live forever, was just diagnosed with this incurable stomach condition.  Yahoo Health

Common Rheumatological Symptoms

Joint Pain (Arthralgia) — Persistent discomfort or soreness in one or more joints caused by inflammation, wear and tear, or underlying autoimmune responses.
Morning Stiffness — Reduced joint mobility and tightness upon waking, often lasting over 30 to 60 minutes in inflammatory conditions like rheumatoid arthritis.
Joint Swelling and Edema — Visible enlargement of affected joints resulting from fluid accumulation in the synovial membrane and inflamed surrounding tissue.
Localized Warmth and Redness — Elevated temperature and erythema skin discoloration surrounding inflamed joints due to increased blood flow from localized inflammation.
Systemic Fatigue — Overwhelming exhaustion and lack of energy caused by ongoing chronic inflammatory cytokine activity throughout the body.
Raynaud's Phenomenon — Temporary color changes in fingers or toes turning white, blue, and red in response to cold or stress due to vascular spasms.
Malar or Butterfly Rash — Red or purplish facial rash spanning across the bridge of the nose and cheeks, classically associated with systemic lupus erythematosus.

Milestones in Rheumatology History

c. 400 BC: Hippocratic Corpus Coining — Hippocrates uses the term "rheuma" to describe body humors flowing into joints, establishing the early classical concept of joint inflammation.
1592: Formal Definition of Rheumatism — French physician Guillaume de Baillou introduces the modern term "rheumatism" to distinguish systemic acute arthritis from localized gout.
1800: Clinical Description of Rheumatoid Arthritis — Augustin Jacob Landré-Beauvais publishes the first detailed clinical description separating rheumatoid arthritis from gout, calling it "asthenic gout."
1859: Naming of Rheumatoid Arthritis — Sir Alfred Baring Garrod formally coins the term "rheumatoid arthritis" to clearly differentiate the inflammatory autoimmune condition from osteoarthritis and gout.
1940: Discovery of the Rheumatoid Factor — Erik Waaler discovers autoantibodies in the blood of patients with rheumatoid arthritis, laying the groundwork for serological autoimmune diagnostics.
1948: Introduction of Corticosteroid Therapy — Philip Hench and Edward Kendall demonstrate the dramatic anti-inflammatory effects of Compound E (cortisone) in treating rheumatoid arthritis, earning the Nobel Prize.
1998: Emergence of Biologic DMARDs — The FDA approves the first TNF-alpha inhibitors, ushering in the modern era of targeted biologic therapies for autoimmune rheumatic diseases.

Current Trends in Rheumatology Research

Chimeric Antigen Receptor (CAR) T-Cell Reset Therapy — Investigating engineered cellular therapies to achieve drug-free, durable clinical remissions by completely depleting pathogenic autoantibodies in severe refractory lupus and systemic sclerosis.
Selective TYK2 and Oral JAK Pathway Inhibition — Developing highly targeted, small-molecule oral inhibitors like deucravacitinib that disrupt specific cytokine signaling pathways while minimizing broader off-target side effects.
Targeted Pathogenic T-Cell and B-Cell Depletion — Evaluating novel biologics, such as rosnilimab and ianalumab, designed to selectively deplete overactive immune cell subpopulations involved in rheumatoid arthritis and Sjögren's disease.
Biomarker-Driven Precision Medicine — Utilizing pharmacogenomics and molecular biomarkers to predict individualized therapeutic responses and match systemic autoimmune conditions to specific biological mechanisms.
Subclinical Interception and Disease Prevention — Identifying seropositive individuals early using high-risk autoantibody profiles to initiate preventive targeted therapies before irreversible joint damage occurs.
Artificial Intelligence and Predictive Disease Modeling — Deploying machine learning algorithms across electronic health records and imaging modalities to forecast inflammatory flares and refine diagnostic accuracy.