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            * Rheumatology101 SEARCH *

                *Filter: "Tendonitis"

      

    Tendonitis: Symptoms, Causes & Treatment - Cleveland Clinic
    Tendonitis (tendinitis) is a condition where the connective tissues between your muscles and bones (tendons) inflame. Often caused by repetitive activities, tendonitis can be painful.

    Tendinitis - Symptoms and causes - Mayo Clinic
    Tendinitis is new or sudden swelling and irritation, called inflammation, of a tendon. Tendons are thick fibrous cords that attach muscle to bone. Tendinitis causes pain and tenderness just outside a joint. Tendinitis can happen in any tendon. It's common around shoulders, elbows, wrists, hips, knees and heels.

    Why Tendonitis Happens and How to Recover - Verywell Health
    Learn how repetitive stress injuries cause tendonitis, the common symptoms, and treatment options to ease pain and restore function.

    Tendinitis - Diagnosis and treatment - Mayo Clinic
    Often, a physical exam alone can diagnose tendinitis. Your healthcare professional may press on the affected joint and move the joint into different positions. Sometimes your healthcare professional may use imaging tests to help with diagnosis. Imaging tests may include: X-rays.

    Tendinitis (Tendonitis): Types, symptoms, causes, and Treatment
    Tendinitis (also called tendonitis) is a condition that occurs when a tendon — the tough cord that connects muscle to bone — becomes inflamed or irritated. It’s commonly caused by repetitive motion or overuse and often affects areas such as the shoulders, elbows, wrists, knees, and heels.

    How to Treat Tendonitis: 5 Home Remedies + When to Seek Help - wikiHow
    Tendinitis is inflammation of the tendons, which are the tapered ends of muscles that attach to bones. Tendons are in action every time muscles contract and bones move. As such, tendonitis is often the result of overuse, such as repetitive movements at work.

    Tendonitis - Johns Hopkins Medicine
    Tendonitis is an inflammation of a tendon—the tough cord of tissue that connects muscles to bones. Tendonitis can affect any tendon, but is most commonly seen in the wrist and fingers.

    Tendonitis - NHS
    Video: What is tendonitis? This animation explains what tendonitis is and what causes it.

    Tendonitis (Tendinitis): Causes, Symptoms & Treatments
    Tendonitis occurs when the tendons become inflamed or irritated. Click here to learn more about what causes tendonitis and how it’s diagnosed and treated.

    Why Your Tendon Pain Won’t Heal – Tendonitis vs Tendinosis
    Many people are told they have tendonitis, but long lasting tendon pain is often something different: tendinosis. Knowing the difference is the first step toward finally healing.

     

     

     

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    Common Rheumatological Symptoms
    • Joint Pain (Arthralgia) — Persistent discomfort or soreness in one or more joints caused by inflammation, wear and tear, or underlying autoimmune responses.
    • Morning Stiffness — Reduced joint mobility and tightness upon waking, often lasting over 30 to 60 minutes in inflammatory conditions like rheumatoid arthritis.
    • Joint Swelling and Edema — Visible enlargement of affected joints resulting from fluid accumulation in the synovial membrane and inflamed surrounding tissue.
    • Localized Warmth and Redness — Elevated temperature and erythema skin discoloration surrounding inflamed joints due to increased blood flow from localized inflammation.
    • Systemic Fatigue — Overwhelming exhaustion and lack of energy caused by ongoing chronic inflammatory cytokine activity throughout the body.
    • Raynaud's Phenomenon — Temporary color changes in fingers or toes turning white, blue, and red in response to cold or stress due to vascular spasms.
    • Malar or Butterfly Rash — Red or purplish facial rash spanning across the bridge of the nose and cheeks, classically associated with systemic lupus erythematosus.

      

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    Milestones in Rheumatology History
    • c. 400 BC: Hippocratic Corpus Coining — Hippocrates uses the term "rheuma" to describe body humors flowing into joints, establishing the early classical concept of joint inflammation.
    • 1592: Formal Definition of Rheumatism — French physician Guillaume de Baillou introduces the modern term "rheumatism" to distinguish systemic acute arthritis from localized gout.
    • 1800: Clinical Description of Rheumatoid Arthritis — Augustin Jacob Landré-Beauvais publishes the first detailed clinical description separating rheumatoid arthritis from gout, calling it "asthenic gout."
    • 1859: Naming of Rheumatoid Arthritis — Sir Alfred Baring Garrod formally coins the term "rheumatoid arthritis" to clearly differentiate the inflammatory autoimmune condition from osteoarthritis and gout.
    • 1940: Discovery of the Rheumatoid Factor — Erik Waaler discovers autoantibodies in the blood of patients with rheumatoid arthritis, laying the groundwork for serological autoimmune diagnostics.
    • 1948: Introduction of Corticosteroid Therapy — Philip Hench and Edward Kendall demonstrate the dramatic anti-inflammatory effects of Compound E (cortisone) in treating rheumatoid arthritis, earning the Nobel Prize.
    • 1998: Emergence of Biologic DMARDs — The FDA approves the first TNF-alpha inhibitors, ushering in the modern era of targeted biologic therapies for autoimmune rheumatic diseases.
    Current Trends in Rheumatology Research
    • Chimeric Antigen Receptor (CAR) T-Cell Reset Therapy — Investigating engineered cellular therapies to achieve drug-free, durable clinical remissions by completely depleting pathogenic autoantibodies in severe refractory lupus and systemic sclerosis.
    • Selective TYK2 and Oral JAK Pathway Inhibition — Developing highly targeted, small-molecule oral inhibitors like deucravacitinib that disrupt specific cytokine signaling pathways while minimizing broader off-target side effects.
    • Targeted Pathogenic T-Cell and B-Cell Depletion — Evaluating novel biologics, such as rosnilimab and ianalumab, designed to selectively deplete overactive immune cell subpopulations involved in rheumatoid arthritis and Sjögren's disease.
    • Biomarker-Driven Precision Medicine — Utilizing pharmacogenomics and molecular biomarkers to predict individualized therapeutic responses and match systemic autoimmune conditions to specific biological mechanisms.
    • Subclinical Interception and Disease Prevention — Identifying seropositive individuals early using high-risk autoantibody profiles to initiate preventive targeted therapies before irreversible joint damage occurs.
    • Artificial Intelligence and Predictive Disease Modeling — Deploying machine learning algorithms across electronic health records and imaging modalities to forecast inflammatory flares and refine diagnostic accuracy.

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