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Search Filter: "vasculitis"

Vasculitis - Symptoms and causes - Mayo Clinic
People who have conditions in which their immune systems attack their own bodies by mistake may be at higher risk of vasculitis. These conditions include lupus, rheumatoid arthritis and scleroderma.

Vasculitis: Symptoms, Types & Treatment - Cleveland Clinic
Vasculitis is an autoimmune disease that causes inflammation in your blood vessels. The swelling makes it hard for blood to flow through your affected vessels, which can cause organ and tissue damage.

Vasculitis - Wikipedia
Vasculitis is primarily caused by leukocyte migration and resultant damage. Although both occur in vasculitides, inflammation of veins (phlebitis) or arteries (arteritis) on their own are separate entities.

Vasculitis - Diagnosis and treatment - Mayo Clinic
A corticosteroid medicine, such as prednisone (Rayos), is the most common type of medicine prescribed to control the inflammation of vasculitis. Corticosteroids can have bad side effects.

Rheumatoid Vasculitis: How It's Treated - WebMD
Vasculitis is the general term for several conditions that cause blood vessel inflammation. Doctors organize vasculitis into types based on the size of the blood vessels involved.

What Is Vasculitis? - NHLBI, NIH
Learn about symptoms, risk factors, and treatments for vasculitis, a group of rare conditions that cause damage to your blood vessels.

Types of Vasculitis : Johns Hopkins Vasculitis Center
There are approximately 20 different disorders that are classified as “vasculitis”. “ Angiitis ” and “ Arteritis ” are both synonyms for vasculitis, literally meaning “inflammation within blood vessels” or “inflammation in arteries.”

Vasculitis - NHS
Vasculitis is the name of a group of conditions that cause inflammation of the blood vessels. Inflammation is your immune system's natural response to injury or infection. It causes swelling and can help the body deal with invading germs.

Symptoms of Vasculitis - Johns Hopkins Vasculitis Center
The term “vasculitis” refers to a group of inflammatory diseases that cause inflammation centered in the wall of blood vessels. This vascular inflammation ultimately leads to damage and dysfunction of the organs that contain the affected vessels.

Rheumatoid Vasculitis: Symptoms & Treatment - Cleveland Clinic
Rheumatoid vasculitis is a type of vasculitis (blood vessel inflammation). It affects people who’ve had rheumatoid arthritis (RA) for a long time (usually 10 years or more). It causes skin rashes, sores and discoloration, usually on or around your fingers, hands, feet and toes.

* Rheumatology101 News Today

          News Filter: "vasculitis"

Improving communication with doctors means trusting ourselves as patients  ANCA Vasculitis News
Q&A: Phase-Specific Relapse Predictors in ANCA-Associated Vasculitis  Physician's Weekly
There’s No Debating the Value of Vasculitis Summit on Webcast  Cleveland Clinic
Who Should Be on Your ANCA-Associated Vasculitis Medical Treatment Team?  Everyday Health
Young researcher joins her childhood doctor in fight against rare kidney disease  Kidney Research UK
After Her Nose Collapsed, Doctors Removed It. She Now Has a ‘Selection’ of Prosthetics to Wear  People.com
How to Travel Confidently When You Live With ANCA-Associated Vasculitis  Everyday Health
Solving for ANCA-Associated Vasculitis  HealthCentral
“I’m Worth the Hassle”: How One Woman with Vasculitis Takes Charge of Her Care  Amgen
Ashton Kutcher Likely Had an ‘Extremely Severe’ Form of Vasculitis, Doctor Explains  Rolling Stone
Which Specialists Treat Your ANCA-Associated Vasculitis (AAV)?  Everyday Health
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review  American Academy Of Family Physicians | AAFP
Mayo Clinic Minute: What is Takayasu’s arteritis?  Mayo Clinic News Network
Ask the Experts: Living With ANCA-Associated Vasculitis  HealthCentral
Is it Vasculitis or Something More?  Cleveland Clinic

Common Rheumatological Symptoms

Joint Pain (Arthralgia) — Persistent discomfort or soreness in one or more joints caused by inflammation, wear and tear, or underlying autoimmune responses.
Morning Stiffness — Reduced joint mobility and tightness upon waking, often lasting over 30 to 60 minutes in inflammatory conditions like rheumatoid arthritis.
Joint Swelling and Edema — Visible enlargement of affected joints resulting from fluid accumulation in the synovial membrane and inflamed surrounding tissue.
Localized Warmth and Redness — Elevated temperature and erythema skin discoloration surrounding inflamed joints due to increased blood flow from localized inflammation.
Systemic Fatigue — Overwhelming exhaustion and lack of energy caused by ongoing chronic inflammatory cytokine activity throughout the body.
Raynaud's Phenomenon — Temporary color changes in fingers or toes turning white, blue, and red in response to cold or stress due to vascular spasms.
Malar or Butterfly Rash — Red or purplish facial rash spanning across the bridge of the nose and cheeks, classically associated with systemic lupus erythematosus.

Milestones in Rheumatology History

c. 400 BC: Hippocratic Corpus Coining — Hippocrates uses the term "rheuma" to describe body humors flowing into joints, establishing the early classical concept of joint inflammation.
1592: Formal Definition of Rheumatism — French physician Guillaume de Baillou introduces the modern term "rheumatism" to distinguish systemic acute arthritis from localized gout.
1800: Clinical Description of Rheumatoid Arthritis — Augustin Jacob Landré-Beauvais publishes the first detailed clinical description separating rheumatoid arthritis from gout, calling it "asthenic gout."
1859: Naming of Rheumatoid Arthritis — Sir Alfred Baring Garrod formally coins the term "rheumatoid arthritis" to clearly differentiate the inflammatory autoimmune condition from osteoarthritis and gout.
1940: Discovery of the Rheumatoid Factor — Erik Waaler discovers autoantibodies in the blood of patients with rheumatoid arthritis, laying the groundwork for serological autoimmune diagnostics.
1948: Introduction of Corticosteroid Therapy — Philip Hench and Edward Kendall demonstrate the dramatic anti-inflammatory effects of Compound E (cortisone) in treating rheumatoid arthritis, earning the Nobel Prize.
1998: Emergence of Biologic DMARDs — The FDA approves the first TNF-alpha inhibitors, ushering in the modern era of targeted biologic therapies for autoimmune rheumatic diseases.

Current Trends in Rheumatology Research

Chimeric Antigen Receptor (CAR) T-Cell Reset Therapy — Investigating engineered cellular therapies to achieve drug-free, durable clinical remissions by completely depleting pathogenic autoantibodies in severe refractory lupus and systemic sclerosis.
Selective TYK2 and Oral JAK Pathway Inhibition — Developing highly targeted, small-molecule oral inhibitors like deucravacitinib that disrupt specific cytokine signaling pathways while minimizing broader off-target side effects.
Targeted Pathogenic T-Cell and B-Cell Depletion — Evaluating novel biologics, such as rosnilimab and ianalumab, designed to selectively deplete overactive immune cell subpopulations involved in rheumatoid arthritis and Sjögren's disease.
Biomarker-Driven Precision Medicine — Utilizing pharmacogenomics and molecular biomarkers to predict individualized therapeutic responses and match systemic autoimmune conditions to specific biological mechanisms.
Subclinical Interception and Disease Prevention — Identifying seropositive individuals early using high-risk autoantibody profiles to initiate preventive targeted therapies before irreversible joint damage occurs.
Artificial Intelligence and Predictive Disease Modeling — Deploying machine learning algorithms across electronic health records and imaging modalities to forecast inflammatory flares and refine diagnostic accuracy.